Tuesday Trials 5/21/2013

Listed below are some of the on-going clinical trials that are currently recruiting participants.  Some are looking for persons who have dementia, others are looking for caregivers, others are looking for healthy individuals to serve as part of a control group.  Some may offer financial reimbursement for participation, but most do not.  These studies are being coordinated by the National Institute for Health in Bethesda, Md.  As always, if you do choose to participate in one of these studies, please do let us know how it goes so that you may provide an inspiration for others.

Neurovascular MRI in the Assessment of HIV-Associated Neurocognitive Disorders — The purpose of this study is to find out if blood vessel function in the brain contributes to mood and thought disorders in persons who are HIV infected.

Intracerebroventricular 2-Hydroxypropyl-B-Cyclodextrin in Patients With Niemann-Pick Disease, Type C1 — This study will attempt to determine if administration of a drug will be helpful in the treatment of persons with NPD, C1.  (There is currently no approved treatment in the U.S. for this condition.)  Test subjects will be between the ages of 7 and 25 years, diagnosed with NPD, C1.  The medication will be delivered through a reservoir surgically implanted under the scalp.

Deep Brain Stimulation Surgery for Movement Disorders — In this study, a battery-operated neurostimulator (a device similar to a pacemaker) will be surgically implanted in the brains of persons who have Parkinson’s disease, dystonia, and similar movement disorders to block the nerve signals causing these abnormal movements.  These patients will then be followed in order to determine what effects the stimulator has on the disease.  Test subjects should be at least 18 years old.

PET Evaluation of Brain Peripheral Benzodiazepine Receptors using [11C]PBR28 in Neurological Disorders — The purpose of this study is to determine how a particular receptor in the brain is influenced, if at all, by the inflammatory process.  Persons with Frontotemporal dementia, as well as healthy individuals, will be given a battery of tests which may include bloodwork, MRI scans, and PET scans, to determine the relationship between FTD and inflammation.

Brain Procurement for the Neuropathology Section, CBDB — The purpose of this study is to obtain brain matter from deceased individuals for further study.  Material is being sought from individuals who were diagnosed with a variety of neurological disorders.  It is hoped that through this work, information may be learned that will be of benefit to others who are struggling with similar problems.


  1. No comments yet.
  1. No trackbacks yet.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s

%d bloggers like this: